Cylinder misfire #5.Checked spark on cylinders 5 and 3.Spark looks the same.Replaced spark plug.Tuned up with new wires and plugs 2 months ago.I am thinking could be coil pack.

Usually if you know which cylinder, you check spark--fuel--compression on that cylinder.
You could do cylinder balance test, engine idling, kill each cylinder, one at a time. If you kill a cylinder that has no effect on rpms, that cylinder is dead for some reason, spark--fuel--compression?
I usually kill spark and do it quickly.

the problem is a sparkplug or wire you must be replaced

What DTC code(s) are you getting?
You performed a compression test on cylinder #1; did you test cylinder #2?
Compare the readings, if there is a significant difference in compression readings between the two, you may have a bad head gasket, a bad valve, etc.
The bottom line, the problem is internal to the engine.

Locate the ignition coils - they are mounted on the ignition module. Remove the wide connector that goes to the module. You will have to unscrew it first. Spray some WD40 on the connector pins and try to scrub them with a tip of a small screwdriver. Be delicate not to brake or bend anything. Reconnect the connector. Start the engine and see if it still misses.
If it still does, try to touch/move each of the wires that go to the ignition module. BE VERY CAREFUL not to touch any of the moving parts of the engine as you have to do it with engine running.

If it still misses, do the following.
1. Engine off
2. Mark the ignition wires so that you reconnect them later in the same order
3. Locate the coil which gives spark for cyl 1
4. Switch locations of this coil with any of the two remaining coils
5. Reconnect the wires
6. Start the engine

If it now misses on another cylinder, you will have to buy a new coil.

For engine misfiring problem check the help links mentioned below. Click the link below to go through the troubleshooting procedure :---- Engine misses and truck jumps? Hard to down shift? Issue with high gear only? http://technoanswers.blogspot.in/2012/02/engine-miss-and-truck-jumps-hard-to.html

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Bad miss at idle?

http://technoanswers.blogspot.com/2012/01/bad-miss-at-idle.html

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While stop engine idles like cylinder missing?

http://schematicsdiagram.blogspot.com/2012/01/while-stop-engine-idles-like-cylinder.html

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Engine Misfire codes for car?

http://schematicsdiagram.blogspot.com/2011/12/engine-misfire-codes-on-chevrolet.html
Engine Misfire codes?

http://schematicsdiagram.blogspot.com/2011/12/engine-misfire-codes-on-chevrolet.html

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Misfire on cylinder 4?

http://schematicsdiagram.blogspot.com/2011/12/misfire-on-cylinder-4.html

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Oil on spark plugs and car misfires?

http://technoanswers.blogspot.in/2012/02/oil-on-spark-plugs-and-car-misfires.html

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This will help.

Thanks.

REPLACE SPARK WIRES THAT COULD BE MISFIRE PROBLEM, ANY TIME OLD SPARK PLUG WIRES IS REMOVED THE WIRES WILL BREAK INSIDE PLUG BOOT CAUSING SPARK PLUG NOT TO FIRE.REPLACE SPARK PLUG WIRES.CLEAN FUEL INJECTORS, CHANGE AIR FILTER,CHECK ALL VACUUM HOSES ON THE INTAKE MANIFOLD LOOKING FOR INTAKE VACUUM LEAKS.

Cylinder #2 is the the second spark plug counting from the right to left.
EX.Below are spark plug on engine
engine
-------------------------------
' (oil cap) '
' (4) (3) (2) (1) '
'_________________'

Your misfire can be cause by couple of things but the cheapest way that you can try to fix your car is to do a tune up by replacing:
1)all spark plugs
2)do a oil change
3)spark plug wires
3)distributor cap and rotor

note misfire can be cause by:
1.bad gas
2.spark plug and/or wire
3.distributor cap and/or rotor
4.valve adjustment
5.injector
6.off timing
7.ECM
8.bad wiring(power, ground or feed line)

A misfire can be related to a number of causes. Since the coil and spark plug were replaced and it did not solve this issue, it is most likely related to the circuit for the number 8 cylinder. A thorough inspection of the electrical circuit is what is required next. Also, engine compression will need to be tested on that cylinder as well as cylinder number 6 that is next to it. Vacuum leak around the intake port of the number 8 cylinder could also be a cause and will need to be checked.

1. Swap two ignition coils between #5 cylinder and another one.
2. If the #5 cylinder misfire problem is still present you must check up wire by wire the electrical supply cable from the Engine Control Module (ECM) to the #5 ignition coil. Repair damaged wire(s). The last piece out of order will be the ECM !
3. Inspect also #5 spark plug if it is wet or dry. If it is dry then you must verify the #5 injector!

WELL destindave i see this was back in 2009 did you ever get it fixed U see I have the same problem.p0303 cylinder 3 I to have checked coils swapt and same chaned plugs and wires and injector and checked compression nothing checked spark at plugs nd coil still misfire in 3 i need help i am at the end