2006 Nissan Titan alternating misfiring and running fine until !

sounds like a dead battery. Disconnect one cable for about 5 min and then re-connect it. That will reset the ECM.

P0300 is random misfire code P0301 would be cyl # 1 etc.
With the odb2 scanner at erase codes turn the engine off. With the key in the run position erase the codes. Run the diagnostics again. If you still have P0300 code Check the plug wires. Loss of compression will cause misfire but it would not be random.

Some cars have an anti theft that cuts the initial fuel off, the will run for a little Until you restart and then it won't start

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Give me some more information about this problem. May be i can help.

2006 NISSAN TITAN ELECTRICAL SYSTEM:BATTERY
Occurences: 1 NISSAN NORTH AMERICA, INC.
Recived: 2007-09-20 Summary: 2006 NISSAN TITAN BATTERY DIED WHILE DRIVING. CUSTOMER STATED THAT HE HAD NO PRIOR INDICATIONS BEFORE THE FAILURE. HE ASKED TO BE REIMBURSED FOR THE BATTERY . *KB THE CONSUMER STATED A BATTERY... The following ELECTRICAL SYSTEM:BATTERY complaint about 2006 NISSAN TITAN was reported to the National Highway Traffic Safety administration on 2007-09-20. For more information contact the National Highway Traffic Safety administration or the US Department of Transportation. See complaint summary below.

Build Years/Makes/Models: 2006 NISSAN TITAN
Occurances:
Reference Number: 10203844
Summary: 2006 NISSAN TITAN BATTERY DIED WHILE DRIVING. CUSTOMER STATED THAT HE HAD NO PRIOR INDICATIONS BEFORE THE FAILURE. HE ASKED TO BE REIMBURSED FOR THE BATTERY . *KB THE CONSUMER STATED A BATTERY SHOULD LAST MORE THAN 11 MONTHS. *JB
Build Years/Makes/Models: 2006 NISSAN TITAN
Occurances:
Reference Number: 10203844
Summary: 2006 NISSAN TITAN BATTERY DIED WHILE DRIVING. CUSTOMER STATED THAT HE HAD NO PRIOR INDICATIONS BEFORE THE FAILURE. HE ASKED TO BE REIMBURSED FOR THE BATTERY . *KB THE CONSUMER STATED A BATTERY SHOULD LAST MORE THAN 11 MONTHS. *JB


2006 NISSAN TITAN
Occurances:
Reference Number: 10203844
Summary: 2006 NISSAN TITAN BATTERY DIED WHILE DRIVING. CUSTOMER STATED THAT HE HAD NO PRIOR INDICATIONS BEFORE THE FAILURE. HE ASKED TO BE REIMBURSED FOR THE BATTERY . *KB THE CONSUMER STATED A BATTERY SHOULD LAST MORE THAN 11 MONTHS. *JB
2006 NISSAN TITAN
Occurances:
Reference Number: 10203844
Summary: 2006 NISSAN TITAN BATTERY DIED WHILE DRIVING. CUSTOMER STATED THAT HE HAD NO PRIOR INDICATIONS BEFORE THE FAILURE. HE ASKED TO BE REIMBURSED FOR THE BATTERY . *KB THE CONSUMER STATED A BATTERY SHOULD LAST MORE THAN 11 MONTHS. *JB
2006 NISSAN TITAN BATTERY DIED WHILE DRIVING. CUSTOMER STATED THAT HE HAD NO PRIOR INDICATIONS BEFORE THE FAILURE. HE ASKED TO BE REIMBURSED FOR THE BATTERY . *KB THE CONSUMER STATED A BATTERY SHOULD LAST MORE THAN 11 MONTHS. *JB
CHECK WITH ANY DEALERSHIP AND GIVE THEM THE VIN NUMBER AND ASK IF THERE ARE ANY TSB'S FOR THIS VEHICLE IF THERE ARE THERE WILL BE FIXED AT NO COST TO YOU

when the engine light flashes it means it detecting a misfire check spark plugs, plug wires , coil, ingition moudle fuel injectors

how many miles does it have , sounds like a rod bearing is bad or has turned , get the knock diagnosed to make sure