Well since you have already eliminated some possible causes now try the ignition module its the plate underneath the coil pack it is not a coil because then it would be misfiring on both cylinders to the coil and 1 goes with 4if this does not solve your problem only one thing left a bad computer causing this problem if you use a scanner you will see it actually is detecting the misfire through the injectors and that means the injector drivers in the computer are worn out. i have seen this several times and when you replace the computer it will have to be reprogrammed by a chevy dealer because the anti theft will not allow it to start . hope this helps you.
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